Bibs Cleidocranial dysplasia (CCD) is a rare congenital defect, primarily affecting bones, undergoing intramembranous ossification.CCD presents with skeletal defects of several bones, the most striking feature of which are partial or complete absence of clavicles, late fontanels closure, and presence of open skull sutures and multiple wormian bones
Objective: This study aims to investigate the prevalence and types of drug resistance mutations among patients failing first-line antiretroviral therapy (ART).Methods: Plasma samples from 112 patients with human immunodeficiency virus-1 (HIV-1) were collected for virus RNA extract and gene amplification.The mutations related to drug resistance were
The mammalian liver plays a key role for metabolism and detoxification of xenobiotics in the body.The corresponding biochemical processes are typically subject to spatial variations at different length scales.Zonal enzyme expression along sinusoids leads to zonated metabolization already in the healthy state.Pathological states of the liver may inv
The process of formation of the Russian emigrant colony in the South French city of Toulon in the period between world wars is considered.The relevance and novelty of this study is determined by the fact that it is based on an extensive Cough Drops set of archival documents, first introduced into scientific circulation, the history of the formation